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Akshay S Desai Selected Research

Spironolactone (Aldactone)

1/2022Prognostic Impact of Cardiovascular Versus Noncardiovascular Hospitalizations in Heart Failure With Preserved Ejection Fraction: Insights From TOPCAT.
1/2021Spironolactone in Patients With Heart Failure, Preserved Ejection Fraction, and Worsening Renal Function.
12/2020Associations Between Depressive Symptoms and HFpEF-Related Outcomes.
1/2020Mechanistic Effects of Spironolactone on Cardiovascular and Renal Biomarkers in Heart Failure With Preserved Ejection Fraction: A TOPCAT Biorepository Study.
12/2019Influence of Age on Efficacy and Safety of Spironolactone in Heart Failure.
1/2019Utility of the Cardiovascular Physical Examination and Impact of Spironolactone in Heart Failure With Preserved Ejection Fraction.
1/2019Efficacy and Safety of Spironolactone in Patients With HFpEF and Chronic Kidney Disease.
11/2018Prognostic Value of Albuminuria and Influence of Spironolactone in Heart Failure With Preserved Ejection Fraction.
11/2018The frailty syndrome and outcomes in the TOPCAT trial.
5/2018Incident Hyperkalemia, Hypokalemia, and Clinical Outcomes During Spironolactone Treatment of Heart Failure With Preserved Ejection Fraction: Analysis of the TOPCAT Trial.
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Akshay S Desai Research Topics

Disease

157Heart Failure
10/2022 - 08/2006
14Chronic Renal Insufficiency
10/2020 - 12/2009
14Hyperkalemia
10/2019 - 11/2007
13Type 2 Diabetes Mellitus (MODY)
01/2022 - 10/2011
13Cardiomyopathies (Cardiomyopathy)
01/2022 - 12/2004
9Diabetes Mellitus
01/2022 - 11/2015
9Heart Arrest (Cardiac Arrest)
01/2022 - 12/2012
9Cardiovascular Diseases (Cardiovascular Disease)
01/2021 - 12/2012
7Anemia
04/2022 - 10/2011
7Myocardial Infarction
01/2022 - 12/2004
6Sudden Death
01/2022 - 12/2004
6Atrial Fibrillation
01/2022 - 01/2018
6Chronic Obstructive Pulmonary Disease (COPD)
12/2021 - 12/2017
6Hypotension (Low Blood Pressure)
10/2019 - 12/2012
6Hypokalemia
01/2019 - 09/2013
6Stroke (Strokes)
01/2018 - 12/2012
5Heart Diseases (Heart Disease)
01/2022 - 12/2014
4Systolic Heart Failure
04/2022 - 03/2013
4Coronary Artery Disease (Coronary Atherosclerosis)
01/2018 - 12/2012
4Chronic Kidney Failure (Chronic Renal Failure)
04/2016 - 11/2011
3Cardiac Sudden Death (Sudden Cardiac Arrest)
10/2020 - 12/2004
3Respiratory Sounds (Crackle)
01/2019 - 09/2013
3Albuminuria
11/2018 - 09/2011
3Fibrosis (Cirrhosis)
05/2017 - 01/2010
2Human Influenza (Influenza)
01/2021 - 02/2016
2Death (Near-Death Experience)
12/2019 - 01/2018
2Angioedema
10/2019 - 09/2014
2Atherosclerosis
05/2019 - 01/2019
2Edema (Dropsy)
01/2019 - 01/2019
2Frailty
11/2018 - 01/2018
2Insulin Resistance
01/2017 - 01/2011
2Left Ventricular Dysfunction
07/2014 - 09/2013
1Cardiac Arrhythmias (Arrythmia)
01/2022
1Shock
01/2022
1Hypercholesterolemia
01/2022
1Neoplasms (Cancer)
01/2021
1Pneumonia (Pneumonitis)
01/2021

Drug/Important Bio-Agent (IBA)

41sacubitril and valsartan sodium hydrate drug combinationIBA
01/2022 - 07/2014
37Mineralocorticoid Receptor AntagonistsIBA
01/2022 - 12/2009
28Neprilysin (Neutral Endopeptidase)IBA
12/2021 - 09/2013
26EnalaprilFDA LinkGeneric
01/2022 - 07/2014
22Brain Natriuretic Peptide (Natrecor)FDA Link
01/2022 - 09/2011
22Spironolactone (Aldactone)FDA LinkGeneric
01/2022 - 11/2007
22Angiotensin Receptors (Angiotensin II Receptor)IBA
12/2021 - 09/2013
22Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
01/2021 - 11/2007
15Natriuretic PeptidesIBA
01/2022 - 01/2013
15CreatinineIBA
12/2021 - 11/2007
14pro-brain natriuretic peptide (1-76)IBA
01/2022 - 09/2011
12Biomarkers (Surrogate Marker)IBA
01/2022 - 10/2011
11dapagliflozinIBA
01/2022 - 01/2019
11PotassiumIBA
01/2021 - 11/2007
10DiureticsIBA
01/2022 - 06/2008
10Angiotensin Receptor AntagonistsIBA
12/2021 - 12/2009
10aliskirenFDA Link
10/2020 - 02/2012
9paragonIBA
01/2022 - 01/2017
8Darbepoetin alfa (Aranesp)FDA Link
04/2022 - 10/2011
8candesartanIBA
08/2021 - 11/2007
7IrbesartanFDA LinkGeneric
08/2021 - 03/2010
6SodiumIBA
12/2021 - 12/2017
6AngiotensinsIBA
01/2021 - 09/2014
5Glucose (Dextrose)FDA LinkGeneric
11/2021 - 01/2011
5Pharmaceutical PreparationsIBA
01/2019 - 11/2007
5Hemoglobins (Hemoglobin)IBA
05/2018 - 03/2013
4Troponin T (Troponin T1)IBA
01/2022 - 10/2011
4Valsartan (Vals)FDA Link
12/2021 - 01/2017
4Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
04/2016 - 09/2013
3Insulin (Novolin)FDA Link
01/2019 - 01/2011
3AlbuminsIBA
11/2018 - 09/2011
2Peptides (Polypeptides)IBA
01/2021 - 01/2020
2ReninIBA
01/2021 - 02/2012
2Influenza Vaccines (Influenza Vaccine)FDA Link
01/2021 - 02/2016
2Uric Acid (Urate)IBA
11/2020 - 01/2018
2Sodium-Glucose Transporter 2 InhibitorsIBA
01/2020 - 11/2019
2Sodium Potassium Chloride Symporter Inhibitors (Loop Diuretics)IBA
01/2020 - 01/2019
2Sodium-Glucose Transport ProteinsIBA
11/2019 - 01/2019
2Thyroid HormonesIBA
05/2019 - 01/2019
2Trinitrotoluene (TNT)IBA
01/2019 - 11/2011
2TroponinIBA
11/2018 - 01/2018
2Renin InhibitorsIBA
04/2016 - 12/2012
1IronIBA
04/2022
1CytokinesIBA
04/2022
1Ferritins (Ferritin)IBA
04/2022
1Growth Differentiation Factor 15IBA
04/2022
1oxidized low density lipoproteinIBA
01/2022
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2022
1empagliflozinIBA
11/2021
1Galectin 3 (LGALS3)IBA
01/2021

Therapy/Procedure

59Therapeutics
10/2022 - 12/2004
7Implantable Defibrillators (Implantable Cardioverter-Defibrillator)
01/2022 - 12/2004
4Defibrillators (Defibrillator)
01/2022 - 12/2004
4Palliative Care (Palliative Therapy)
01/2021 - 01/2018
4Patient Readmission
01/2020 - 08/2003
3Transplantation
09/2015 - 11/2012
2Cardiac Resynchronization Therapy
01/2022 - 01/2020
2Drug Tapering
01/2019 - 11/2007
2Heart Transplantation (Grafting, Heart)
01/2015 - 01/2010
2Heart-Assist Devices
01/2014 - 01/2010
2Renal Replacement Therapy (Therapies, Renal Replacement)
12/2012 - 11/2011
1Coronary Artery Bypass (Coronary Artery Bypass Surgery)
12/2021
1Polypharmacy
11/2021